Physician Salary in Mississippi: $193K Median

The average Physician salary in Mississippi is $192,612 per year as of April 2026. Salaries range from $147,000 (entry, 25th percentile) up to $336,000 (90th percentile). State income tax applies.

Physicians in Mississippi earn approximately 16% less than the US national median ($229,300 nationally vs $192,612 in Mississippi). Mississippi's cost-of-living index of 85 amplifies the real purchasing power.

Yes — Physician salaries in Mississippi grew approximately 560.0% year-over-year, from $29,184 in 2025 to $192,612 in 2026. This reflects the broader Healthcare sector's wage growth, driven by Telemedicine and AI-assisted diagnosis demand.

Mississippi has no major metros in our database — fallback to the closest tracked city for detailed breakdowns.

Physician demand strong with growing US population. Specialties like radiology, anesthesiology, and orthopedics paying $400K+. Mississippi's top industries include Manufacturing, Agriculture, Healthcare, and the state's unemployment rate is 3.5% — a tight labor market favoring candidates.

Yes, Mississippi has state income tax. This affects take-home pay — at $192,612, expect 4-7% effective state tax depending on filing status. See city pages for detailed take-home calculations.

Hottest 2026 skills: Telemedicine, AI-assisted diagnosis, Concierge medicine, Specialty practice, EHR efficiency. ATS systems specifically scan for these. Adding them to your resume — naturally and in context — improves your match rate with Mississippi employers.

Given the current shortage in this specialty and my certifications, I'm looking for $X base plus shift differential and a sign-on bonus. What flexibility do you have on those line items? Beyond base, negotiate: Sign-on bonus ($10K-$30K, often $50K+ for hard-to-fill roles), Tuition reimbursement and certification stipends, Loan repayment programs (especially federal/HRSA-eligible), Shift differentials (nights +15%, weekends +10%). Walk-away anchor for Mississippi: $175,102.