Nurse Practitioner Salary in Massachusetts: $152K Median

The average Nurse Practitioner salary in Massachusetts is $151,618 per year as of April 2026. Salaries range from $112,100 (entry, 25th percentile) up to $206,500 (90th percentile). State income tax applies.

Nurse Practitioners in Massachusetts earn approximately 18% more than the US national median ($128,490 nationally vs $151,618 in Massachusetts). Massachusetts's cost-of-living index of 130 partially offsets the higher salary.

Yes — Nurse Practitioner salaries in Massachusetts grew approximately 560.0% year-over-year, from $22,972 in 2025 to $151,618 in 2026. This reflects the broader Healthcare sector's wage growth, driven by Telehealth NP and Mental health (PMHNP) demand.

Top-paying Massachusetts metros for Nurse Practitioners: Boston ($167K). Click any city for full breakdown including take-home pay.

NP roles growing 38% through 2034 — among fastest-growing US occupations. Full practice authority in 27 states drives demand. Massachusetts's top industries include Biotech/Pharma, Higher Education, Healthcare, and the state's unemployment rate is 3.7% — a tight labor market favoring candidates.

Yes, Massachusetts has state income tax. This affects take-home pay — at $151,618, expect 4-7% effective state tax depending on filing status. See city pages for detailed take-home calculations.

Hottest 2026 skills: Telehealth NP, Mental health (PMHNP), Pediatric NP, Geriatric NP, Full practice authority states. ATS systems specifically scan for these. Adding them to your resume — naturally and in context — improves your match rate with Massachusetts employers.

Given the current shortage in this specialty and my certifications, I'm looking for $X base plus shift differential and a sign-on bonus. What flexibility do you have on those line items? Beyond base, negotiate: Sign-on bonus ($10K-$30K, often $50K+ for hard-to-fill roles), Tuition reimbursement and certification stipends, Loan repayment programs (especially federal/HRSA-eligible), Shift differentials (nights +15%, weekends +10%). Walk-away anchor for Massachusetts: $137,835.